Diseases in women due to immunodeficiency

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Diseases in women due to immunodeficiency

If the dust with the odor goes inside it will be filtered through the nostrils. If it goes through the mouth, it is digested or vomiting and comes out as waste. If it falls on the eyes the tears will multiply and cleanse and push out. If it tries to get into the ear it will get stuck in the wax which looks like glue. However, such as bacteria and virus can enter the body through contaminated food, water, wounds, and mosquito bites.

Immune System:

·        Mucous membranes

·        Adenoids

·        Tonsils

·        Right lymphatic duct

·        Thoracic duct

·        Lymphatic vessels (Neck)

·        Thymus

·        Lymph nodes: Cervical lymph nodes, Axillary lymph nodes, Inguinal lymph

       nodes, Popliteal lymph nodes.

·        Peyer’s patches – located throughout small intestine

·        Appendix

·        Skin

·        Spleen

·        Lymphatic vessels (Lower limb).

Bone marrow, thymus gland, white blood cells, spleen and lymph nodes play an important role in the immune system. Everything that enters the body is tested and allowed by the power of genetic codes.

White blood cell, so called leukocyte or white corpuscle, a cellular component of the blood that lacks hemoglobin, has a nucleus, is capable of motility, and defends the body against infection and disease by ingesting foreign materials and cellular debris, by destroying infectious agents and cancer cells, or by producing antibodies.

In adults, the bone marrow produces 60 to 70 percent of the white cells. White cells are highly differentiated for their specialized functions, and they do not undergo cell division in the bloodstream; however, some retain the capability of mitosis.

Lymphocytes, which are further divided into B cells and T cells, are accountable for the specific recognition of foreign agents and their subsequent removal from the host. Typically, T cells recognize virally infected or cancerous cells and destroy them, or they serve as helper cells to assist the production of antibody by B cells.

Emerging functions of the immune system in regulating complex tissue physiology:

	Normal physiology	Pathological effects
Heart	Electrical conductivity in cardiomyocytes, tissue repair.	Fibrosis.
White adipose tissue	Bulging of WAT, Thermogenesis, Lipolysis, Insulin sensitivity.	Inflammation, Obesity, Insulin resistance.
Skeletal muscle	Myogenesis, Tissue regeneration, FAP activation.	Fibrosis.
CNS	Sociability, Synaptic trimming.	Neuro inflammation, Sickness behavior, ASD- like behavior, Loss of learning and cognition.
Brown adipose tissue	Thermogenesis Innervation.
Gastrointestinal tract	Intestinal peristalsis, Neuropeptide production, Microbiota composition, Nutrient availability, Epithelial integrity.	IBS, Intestinal barrier infection, Microbial dysbiosis.

Auto immune system:

It is natural for immunity to decline with age. The immune system accidentally attacking the body instead of protecting it. When the body’s natural defense system can’t tell the difference between own cells and foreign cells, causing the body to mistakenly attack normal cells. There are over 100 known autoimmune diseases.

Systemic lupus erythematosus:

Systemic lupus erythematosus is an autoimmune illness that affects many organs and systems in the body. Lupus is a chronic condition, but symptoms tend to cycle in alternate periods of flares and remissions.

Symptoms of systemic lupus erythematosus:

·        Fatigue.

·        Fever.

·        Butterfly – shaped rash on the face that covers the cheeks and bridge of the nose or rashes elsewhere on the body.

·        Joint pain, stiffness and swelling.

·        Skin lesions that appear or worsen with sun exposure.

·        Headache

·        Chest pain when inhaling deeply caused by inflammation in the lining of the lungs.

·        For some, the symptoms may appear and disappear from time to time.

·        For some it will stop with the hair will stand on end.

·        Some people have hyperpigmentation on the face.

·        If it attacks the kidneys, its filtering function is impaired and protein from the blood is excreted in the urine, causing Nephrotic Syndrome. The body swells. Kidney failure can occur if left untreated.

Thyroid disorders:

Hyperthyroidism (Overactive thyroid), also known as Graves’ disease affects women more. The thyroid gland secretes excessively. An eye disease called Graves’ ophthalmopathy. It can cause double vision, light sensitivity, and eye pain. It can lead to vision loss.

Hypothyroidism (underactive thyroid) – This attack can cause the thyroid gland to secrete less at times. The name for this is Hashimoto’s thyroiditis (autoimmune thyroiditis). Symptoms of Hashimoto’s thyroiditis include feeling cold, fatigue, depression, dry skin, constipation, joint stiffness and muscle pain and weight gain.

Rheumatoid Arthritis:

If the attack is on the joints coming up is rheumatoid arthritis. Swelling of the joints can cause pain. Symptoms include dizziness, weight loss, fever, eye irritation, and a lump under the wrist. Difficulty walking and climbing stairs.

Liver damage:

Primary biliary cirrhosis is caused by an attack on the liver. The bile ducts are affected. Decreased bilis causes digestive disorders. Due to inflammation of liver decreases hepatic function. Symptoms of Primary Biliary Cirrhosis include dizzy, itchy skin, dry eyes and mouth, fatigue, bone and joint aches, pain or discomfort in the upper right side of their tummy and yellowing of the skin and whites of the eyes.

Dryness of the lips and eyes:

Sjogren’s Syndrome is caused by an attack on the glands that secrete saliva and tears.

Symptoms of Sjogren’s syndrome:

·        swallow or speak.

·        The tongue will go numb.

·        Tooth decay may occur.

·        The voice will change.

·        As well as dry and hot eyes.

Nervous system damage:

Myasthenia Gravis is caused by an attack on the nerves. It is caused by a problem with the signals sent between the nerves and the muscles. The chances of having a stroke are high.

Symptoms of Myasthenia Graves:

·        Drooping of one or both eyelids.

·        Blurred or double vision.

·        Impaired speech.

·        The head does not stand erect.

·        Difficulty swallowing.

·        Fatigue

·        Changes in facial expression.

·        Shortness of breath.

·        Difficulty chewing.

Multiple Sclerosis:

Multiple Sclerosis occurs when the upper part of the nerves is attacked. Myelin sheath attacked and the nervous system may be affected. Hand and foot tremble. There will be difficulty in walking. Numbness develops in the feet.

Platelets Damage:

Platelets play a major role in blood clotting. Idiopathic thrombocytopenic purpura is a blood disorder characterized by an abnormal decrease in the number of platelets in the blood. Excessive bleeding during menstruation. Brown patches appear on the skin. Bleeding from the nose.

Best treatment for Idiopathic thrombocytopenic purpura:

Since spontaneous remissions are uncommon in adults with Idiopathic thrombocytopenic purpura, the administration of glucocorticoids is the recommended treatment when necessary. Prednisone or high-dose dexamethasone, 40mg/day orally for 4 days, repeated every 14-28 days as needed, are the regimens most commonly used.

(Note: Consult a Doctor and take appropriate treatment).

Red blood corpuscles damage:

Hemolytic anemia is a blood condition that occurs when your red blood cells are destroyed faster than they can be replaced. Hemolytic anemia may be caused by inherited conditions that affect the red blood cells.  RBC can carry oxygen throughout the body with the help of hemoglobin. When these are affected, the heart does not get enough oxygen.

Symptoms of Hemolytic Anemia:

·        Pale skin that may start to yellow.

·        Dizziness and lightheadedness may occur.

·        Shortness of breath.

·        Chills.

·        Tachycardia.

·        Chest pain.

·        Dark urine.

Key notes:

v Can come to anyone.

v Negative attacks are more likely to affect women. The reason is that women are naturally more immune than men.

v May come in adolescence.

v In particular, women can be attacked at any time after puberty until the period of menopause.

v Because of the role of genes in this, if one member of the family is likely to come to the other. But that is not to say that the same disease will come.

v Apart from genetics, certain foods and toxins can also trigger this disease.

v Gluten- rich foods can cause diabetes and bowel cancer.

v Excess fat, sugar and salt intake can also affect the immune system. The list goes on and on, with pesticides, fertilizers, vaccines, and chemicals used in processing of dairy and food products.

Diagnosis method:

·        There are no individual tests for this. It can be tracked with symptoms.

·        There may be a delay in confirming that it is an immune deficiency even if various tests are done. The reason is that the symptoms may be caused by other diseases.

·        It is a good idea to take care of any changes in any part of the body and report them to the doctor.

·        There is no expert for this. The nephrologist should be consulted if there is damage to the kidneys. The rheumatologist is the doctor if the joint pain. This is because there can not be a single specialist called an autoimmune specialist for this which is responsible for various diseases.

·        Even if you see a different specialist for each symptom, the presence of an immune deficiency will only become apparent when it affects. That makes it impossible to diagnose the disease at an early stage.

·        According to the ‘American Autoimmune Diseases Association’ reports that it takes an average of 4.6 years for these patients to be diagnosed by different specialists.

·        Because it can attack any organ, there Can be a delay in diagnosing the disease until it is brought to the attention of a particular specialist, even if seen by many doctors.

Treatment:

·        Medications can be given first for symptoms such as pain, swelling, stress, tension and insomnia. Diabetes, hormonal disorders such as thyroid can be treated with appropriate treatment.

·        Medications that control them will be given if it is determined that they are immune deficiency.

Women with immunodeficiency – Child bearing:  

Women with this disease need more attention even though they have no difficulty in having a baby. The reason is that miscarry can occur if there is lupus impact. Women with Myasthenia Gravis may have difficult breathing during childbirth. There will be restrictions on giving multiple medications during pregnancy.

Do’s:

·        A balanced diet is very important for women. Vegetables, fruits, whole grains, low- fat dairy products can be added. Sugar and salt should be in the diet properly.

·        Keeping nails and hands clean will prevent germs from passing through the mouth. Damage to the teeth and gums also affects the immune system, so their hygiene is essential.

·        People with joint pain and physical ailments can do exercises that do not cause physical strain. Yoga is the best.

·        Leaning comfortably in mind-pleasing background music and closing the eyes for 15 minutes and bringing the painful area to the mind’s eye and imaging it as a cure may give the mental courage to face it whether the disease subsides or not.

·        Above all, good rest is very essential. As well as 7 to 9 hours of sleep is essential. Only then will the body be able to repair its weakness and damage automatically.